90 Pushkin st./ 14 Aurora st., Ufa, Russia, 450008
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History of the Institute

State budget institution "Ufa Eye Research Institute " - one of the leading  research institutes of ophthalmology   in Russia, which has more than a century of history. Through the efforts of many scientists and specialists, the institute has a steady reputation as one of the leading institutions of opthalmology of the Russian Federation and the Republic of Bashkortostan.  From 2005 the Institute is headed by Mukharram Bikbov- PhD, Professor, Corresponding Member of the Academy of Sciences of the Republic of Bashkortostan.

 The history of the institute dates back to the second half of the XIX century.

The Ufa Eye Research Institute dates (goes) back to 1886 when the Ufa department of the Guardianship for blind people of empress Maria Aleksandrovna was established.

 Under the supervision of the Guardianship in 1888 Ufa asylum for blind adults and specialized school for blind children were opened.

 

In August, 11, 1901 the school was reorganized into free eye clinic in Ufa with 4 beds. 

Arseniy Belsky (1901-1903) became the first director of the hospital. In subsequent years, the directors of the hospital were Vladimir Sushkin (1903-1904), Anna Meyer (1904-1910 and 1920-1925), Fedor Kirkevich  (1910-1914).


In 1926, in connection with the massive disease of the population of Bashkiria, the Bashkir Trachomatous Research Institute was established on the basis of a 50-bed regional hospital. The first scientific director and organizer was Viktor Odintsov- a leading ophthalmologist, Professor at the 1st Moscow Medical Institute. He headed the institute in 1925-1928. The great merit in the organization of the institute belongs to the first People's Commissar for Health of the Bashkir ASSR G.G. Kuvatov, due to his efforts the institute was equipped with ophthalmic equipment and medical instruments from Germany. In 1928-1932 Vladimir Tabakov was the director of the Bashkir Trachomatous Research Institute , in 1933-1934. - Joseph Agarev .


 

The priority areas of the department for the rehabilitation of persons with injuries of the organ of vision were the study of the pathogenesis of the wound process in eye injuries and their consequences, the development of keratoplasty methods, the surgical treatment of retinal detachment, and new wound healing, absorbing and anti-inflammatory drugs. Conducted closed vitrectomy, removal of parietal foreign bodies, endolasercoagulation, vitreoretinal and sclero strengthening operations during retinal detachment. The surgical technique of giant retinal tears, eye injuries, post-traumatic and diabetic retinopathy was constantly improved, methods of plastic surgery for cicatricial changes of eye appendages and anophthalmos were developed.  

In 1932, the number of beds in the institute increased to 150. Bacteriological and histological laboratories equipped with special equipment were opened. Animal studies were conducted in the vivarium. In 1934, the Institute was headed by Professor V.I. Spassky. From this period a total survey of the population of the republic on trachoma begins, teams of specialists are created, they provide conservative and surgical treatment. The opening of the Department of Eye Diseases at the Bashkir State Medical Institute on the basis of the institute in 1936 expanded the possibilities of conducting research on the prevalence and clinical presentation of trachoma and the implementation of measures to combat it. The first head of the department was Vladimir Spassky (1936-1955). Thanks to his creative, purposeful nature, he successfully engaged in scientific, educational, therapeutic and social activities aimed at improving the population from trachoma and treating its complications. He published scientific papers on the diagnosis and surgical treatment of trachoma. For the enormous contribution to health care V. Spassky was awarded the Order of the Red Banner of Labour and  the Order of Badge of Honor.

A hospital was located at the base of the institute for the treatment of the wounded people during the Great Patriotic War.

In the postwar period (1945-1965), the institute again became the scientific and organizational-methodical center for the prevention and treatment of trachoma and its consequences. A number of applied works of that period formed the basis of the conducted basic research in the field of etiology and pathogenesis of the disease. The Honored Doctor of the Bashkir ASSR and the RSFSR, Honored Science Worker of the RSFSR Gabdulla Kudoyarov made a significant contribution to the fight against trachoma. They achieved good results in the field of bacteriological, virological and morphological studies of trachoma, adenoviral conjunctivitis and spring catarrh. Professor Kudoyarov for achievements in the development of medical science, many years of fruitful work was awarded the Order of Lenin and the Red Banner of Labour. As a result of the massive organized offensive of medical workers and the public by the mid-60s, trachoma was eliminated. A great contribution to the organization of the ophthalmological assistance of the republic was made by researchers and doctors of I.A. Agarev, F.Sh. Kuzyahmetova, N.Kh. Mescherova, A.V. Chubukov, G.A. Valeeva, V.A. Gizatullin, L.P. Nevzorov, F.Sh. Kurbanaeva, R.G. Kudoyarov, R.F. Voishvillo and many others. 

  

In 1965 the Bashkir Trachomatous Research Institute of Eye Diseases was transferred to the Ministry of Health of the RSFSR and reorganized into the Ufa Research Institute of Eye Diseases. The main scientific directions of this period are the study of the influence of petrochemical products on the organ of vision. The mechanisms of eye damage by some products of oil were revealed, and recommendations were developed for identifying, treating and preventing functional changes in the eyes of petrochemical workers (K.R. Belenky, A.H. Giniatullina). At the same time, the problems of viral eye diseases, prevention and treatment of eye injuries, organizational issues of improving the ophthalmological service in the country were investigated.

A large role in attracting talented researchers and creating an employable team of the institute belongs to the leaders who headed the institute at different times: Professor V.P. Odintsov (1926-1934), Professor V.I. Spassky (1934-1944), Professor G.Kh. Kudoyarov (1945-1954), doctor of the highest category M.S. Tanatarova (1955-1958), Ph.D. S.Khalitova (1959-1965), Ph.D. M.A. Kalmetyeva (1965-1980), Professor M.T. Aznabaev (1980-2005). Since 2006, the director of the institute is Professor M.M. Bikbov.

In the 1980s, the institute became an interregional center for microsurgery and laser treatment methods (director - Prof. MT Aznabayev). Along with the training of personnel in microsurgery and laser therapy, new laboratories were created, modern operating microscopes, cryoextractors, phacoemulsifiers, biometers, keratometers, fundus camera, laser systems, machines for the production of contact lenses and artificial lenses, etc. were acquired.

The scientific profile of the institute is the development of problems of pediatric ophthalmology, complex treatment, medical and social rehabilitation of patients with damage to the organ of vision and. The staff of the institute was replenished with young personnel.

Priority was research in the field of congenital cataract surgery. A new concept has been proposed, based on the idea of ​​surgical treatment of congenital cataracts in infants, in order to ensure early inclusion in the work of the visual analyzer and prevent its functional underdevelopment. The possibility of using small surgical incisions has been substantiated, devices, instruments, artificial lenses have been developed, and minimally invasive surgical approaches have been substantiated. New approaches and additions in congenital cataract surgery, retrolental fibroplasia have significantly improved the results of surgical treatment of children. A school of pediatric ophthalmologists has been created and new directions in pediatric congenital ophthalmopathology have been developed. For the series of works "Surgical methods of rehabilitation of congenital lens diseases" a team of researchers of the children's department was awarded the Republican Prize of Creative Youth (1987).

A method of epikeratoplasty for correction of high degree anisometropia in children is proposed, regularities of changes in the refractive power of the cornea during the binding of positive and negative biolins are determined, kerathorrefraction operations, a method of IOL implantation through a tunnel incision, children’s high-capacity reconstructive operations, a procedure, a procedure, and a method for implantation of an IOL through a tunnel incision are developed; bottom in children.

In the Department of Infectious Eye Diseases (headed by Prof. VB Malkhanov), one of the oldest in Russia, methods for the prevention, diagnosis, and pathogenetically oriented treatment of viral, chlamydial, and infectious-allergic eye diseases have been developed, the importance of viremia has been established. Clinical features were determined, measures for diagnosing and treating epidemic keratoconjunctivitis and complicated forms of adenoviral conjunctivitis were developed.

        
Bikbov Muharram
PhD, Professor, 
Corresponding Member of Academy of Sciences of Republic of Bashkortostan;
Director of the Ufa Eye Research Institute    

Currently, the Ufa Research Institute of Eye Diseases is a center for high ophthalmologic technologies, including cataract surgery, retinal and vitreous pathology, refractive surgery. The Institute is a large multidisciplinary institution that carries out scientific, medical and consulting, industrial and educational activities.

Since 2006, profound changes have occurred in the field of scientific research and ophthalmic practice. Currently, the institute employs 109 ophthalmologists and researchers, including 9 doctors and 29 candidates of science, 2 Honored Doctor of the Russian Federation and 9 Honored Doctors of the Republic of Bashkortostan, 51 doctors of the first and highest categories. In the structure of the institute there are research and research and production departments. The research department includes 2 scientific departments: corneal and lens surgery; vitreoretinal and laser surgery. The research and production department includes an engineering department, a laboratory for the production of medical products and an international relations and marketing department.

Main areas of work: 

  • development of a system for complex treatment of corneal pathology and refractive errors;
  • improvement of minimally invasive ultrasound surgery methods for age-related and complicated cataracts;
  • development of surgical, laser and pharmacological methods for the rehabilitation of patients with diseases of the retina and vitreous body;
  • pathogenetically directed technologies in glaucoma surgery, prevention methods;
  • pathogenesis, diagnosis and treatment of congenital and acquired eye disease in children;
  • development of medical products.

The current stage of the Institute’s work is characterized by a significant reorganization of scientific activity with a focus on the development of innovative technologies and the commercialization of the intellectual property of its scientists. Since 2007, the Institute has been planning and implementing innovative projects, developing devices, medicines, and technologies for eye disease surgery. An infrastructure environment for the effective implementation of innovative projects, designed for long-term prospects, was organized. This was preceded by the search, selection and involvement in the work of capable professionals who know how to create new and implement it. In accordance with the Russian program of import substitution, the institute develops and produces medical devices necessary for practical health care, which will reduce the need for foreign products, and in some cases completely replace them. & Nbsp; The scientific and educational department provides irreplaceable assistance in recruitment.

In the process of performing fundamental and applied research on kerathectasies, a department of cornea and lens surgery was created. The main activities are the development of diagnostic methods, technology of surgical and therapeutic methods for treating diseases of the cornea and lens, surgical correction of ametropia, and the creation of medical products. 

A professional approach, an in-depth analysis of surgical results, and a constant study of the experience of colleagues allowed the Institute to create new technologies and introduce them in a number of ophthalmological clinics in Russia and other countries. Thus, the inventions of scientists in the field of ophthalmosurgery gave an aggregate of complete, complete technology for the treatment and rehabilitation of patients with degenerative cornea diseases.

Long-term work of the department staff led to the creation of an ophthalmological device "UFalink" for UV-crosslinking, the therapeutic effect of which is based on correcting the biomechanics of the pathologically changed optical structure of the eye - the cornea. The method contributes to biomechanical stabilization of the cornea with progressive and iatrogenic keratoectasias. The device "UFalink" is certified and registered in the Register of Medical Products of the Russian Federation. The scientific and technical level of the device meets the standards of foreign analogues.Created a device for monitoring the power of ultraviolet radiation UV-tester, corresponding to the requirements of GOST.

Studies at the molecular level have contributed to the development of a new ophthalmologic agent, Dextralink, which is involved in the cornea crosslinking process. Since 2009, the device and the corneoprotector have been mass-produced, repeatedly awarded diplomas and medals of exhibitions, incl. and international. 

Registration of clinical studies “Standard and transepithelial corneal collagen crosslinking methods in treating patients with keratectasias” and “Myoring intrastromal rings implantation combined with corneal collagen crosslinking in patients with keratoconus” in the international database of clinical studies ClinicalTrials.gov PRS (USA) testifies research international standards.

Currently, the institute is actively developing, & nbsp; experimental design samples of a whole range of medical devices are being created, in particular, the UFhallink Quant, devices for ultraviolet irradiation of the cornea of the eye, new types of photosensitizers and corneal and sclera crosslinking devices, ION ionophoresis devices, etc. 

In the department of vitreoretinal and laser surgery, which was established in 2007, endovitreal surgeries are widely used, including using surgery 25 gauge, with ocular complications of diabetes mellitus, hemophthalmus of various etiologies, retinal thrombosis of the vessels. Intravitreal administration of angiogenesis inhibitors is widely used, which is a highly effective method of treating age-related macular degeneration.  

The issues of pathogenesis, diagnosis and treatment of refractory forms of glaucoma are still relevant. Patients with this pathology are implanted at the institute with various types of drainage devices, in particular, the Ahmed valve, the shunt & nbsp; Ex-Press, drainage "Repegel", "Glautex", xenoplast, etc. In the treatment of open-angle glaucoma, canaloplasty is performed. The clinical and functional results of modern technologies of cataract surgery, including using femtosecond laser, polyartifakii method in the correction of residual ametropia in children and adolescents. & nbsp; At the institute, the 25G technique is used in congenital cataract surgery in children, which allows obtaining good anatomical and functional results, reducing the risk of complications. Employees of the Institute deal with the problems of early diagnosis and rehabilitation of children with retinopathy of prematurity and retinoblastomas. 

The first among the state ophthalmologic clinics of our country at the institute began operations using a femtosecond laser for keratoplasty, cataract surgery, incl. congenital in children.

The use of high technology involves training. Since 2007, 7 Doctoral and 27 PhD theses have been defended by the Institute’s employees. Constantly involved young people to research. Repeatedly, young researchers have won republican and Russian grants. The participation of the institute's employees in the work of the All-Russian Youth Educational Forum “Seliger - 2011”, the Youth Innovation Forum of the Republic of Belarus “INNOVA-2011” provided an opportunity to present your project to business and government representatives, listen to unique educational programs, and attract investors. In 2011, a group of young scientists of the institute (PhD GM Bikbova, NE Baymukhametov, AF Habibullin) won the competition for innovative developments and was awarded the State Republican Youth Prize in science and technology. Ph.D. R.R. Fayzrakhmanov and Ph.D. A.L. In 2014, Yarmukhametova won the competition among young scientists and youth teams and was awarded the Grant of the Republic of Bashkortostan for scientific work in the form of the monograph “Age-related macular degeneration”. In 2015, young scientists of the Institute M.R. Kalanov and M.N. Astrelin became the winners of the regional stage of the All-Russian start-up tour, taking respectively I and II places in the section “Biological and Medical Technologies”. Our young employees received not only the opportunity to take part in the final stage of this competition, but also 1 million rubles for the development of innovative ideas. 

The State Prize of the Republic of Bashkortostan in the field of science and technology was awarded for the creation of the Atlas of Eye Pathology for employees of the Institute (Prof. M.T. Aznabayev, Prof. V. B. Malkhanov, MD, N. Nikitin).  

In 2013, the work of MM. Bikbova, G.M. Bikbova "Corneal Ectasia" was awarded the Prize of the Academy of Sciences of the Republic of Belarus. G.H. Kudoyarova. 

For jointly with Japanese scientists to develop a unique drug for the treatment of eye diseases associated with diabetes, Bikbova G.M. She was awarded the European Association for Research on Eyes and Eye Research (EVER). 

The institute closely cooperates with scientific ophthalmological schools of Russia and far abroad: Germany, Austria, Japan, India, etc. There is a constant exchange of experience in the field of mastering and introducing new technologies of surgery for socially significant diseases of the organ of vision. The international scientific and practical conferences East-West are held annually, in which well-known ophthalmologists of Russia and the world take part. Repeatedly an international team of leading experts led by prof. I. Kreissig (Germany) conducted training courses on the diagnosis and treatment of patients with retinal pathology. Broadcasting of "live surgery", the organization of tele-bridges with scientists from cities in Russia and abroad contribute to the professional growth of the institute's specialists and the training of young personnel. The results of the work of scientific schools are published in leading medical journals, monographs, methodical recommendations, and are covered in the mass media. 

International cooperation is carried out in the implementation of joint research projects. Thus, for three years, the institute scientists carried out a joint with Switzerland program “Luminous” for the treatment of patients with age-related macular degeneration. Currently, a joint study is being carried out with scientists from the University of Heidelberg (Germany) and the Royal College (United Kingdom) to identify ophthalmopathology among the population of Ufa and the regions of the Republic of Belarus - the Ufa Eye and Medical Study (UEMS). Together with German ophthalmologists, work continues on treating children with amblyopia using modern computer technology, the results of which are highly appreciated by German ophthalmologists at the congress of the Saxon Ophthalmological Society.

The clinic of the institute is represented by 5 microsurgical departments, an adult and children's consultative polyclinic; functional diagnostics departments; in-patient technology, ambulatory and ambulatory surgery with a laser department.

The provision of medical care in the Ufa Research Institute of Eye Diseases as part of the compulsory health insurance program ensures full access to the most modern ophthalmologic technologies to all residents of the republic and regions of the Russian Federation. The use of high-tech operations in the clinic has been made: femto-assisted surgery of the cornea and the lens, all forms of the region tel, endovitrealnaya technology closing retinal tears, laser surgery, drainage surgery glaucoma, imp Lanta modern models of IOL, including additional lenses for ametropia and premium lenses. 

 Despite the presence of a large number of private ophthalmologic clinics, a large number of patients seek treatment at the institute, which indicates trust in a public institution. including more than 2 thousand - to children. The clinic receives annual consultation of more than 70 thousand people. The number of treated patients with such socially significant diseases as cataracts increased 12 times, retinal diseases - almost 15 times.

All our achievements would have been impossible without a strong and cohesive team of like-minded ophthalmologists seeking to be the best in their profession. And they are. So, the institute's doctors repeatedly became winners of the republican contest “Best Doctor of the Year” in the “Ophthalmologist” nomination. "The best ophthalmologist." A group of employees in the composition of Ph.D. Sh.R. Kuzbekova, Ph.D. A.R. Halimova, S.V. Kharitonov and M.R. Kalanova was recognized as the winners of the republican competition in the nomination “For the creation of a new treatment method” For unique technologies and successful work of the head of the children's microsurgical department, Dr. med. I.S. Zaydullina was recognized as the best ophthalmologist in Russia.

Employees of the institute not only constantly improve their educational level by participating in international congresses and symposia, while studying at leading world clinics, but also try to share their knowledge. Specialists from the Republic of Belarus, Russia, Kazakhstan, Uzbekistan, Azerbaijan, Kyrgyzstan, Syria, Yemen, Germany, Malaysia and other countries study or improve their qualifications on the basis of the scientific and educational department of the institute.

In recent years, a complete reconstruction of the operating rooms and the equipment of the institute’s buildings has been carried out. The range of modern diagnostic ultrasound, immunological, virological, biochemical, and electrophysiological research methods is expanding. & Nbsp; Renewal of the material and technical base of the institute and advanced training of specialists contribute to reducing the number of blind and visually impaired people in the republic and the Russian Federation.

The scientific and clinical contribution of the institute to the development of the republic was noted by the Head of the Republic of Bashkortostan RZ. Khamitov during the solemn event at the International Conference on Ophthalmology "East-West" in 2016  

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